NAD+ is a coenzyme essential for energy production and cell health, linked to anti-aging and biohacking.

Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme found in all living cells. It's central to metabolism and works as a helper molecule, binding to other enzymes to help cause reactions on the molecular level. NAD+ has gained attention for its role in various metabolic processes that are integral to the health of our cells, particularly those related to aging and longevity.

Importance of NAD+ in Medical Aesthetics and Biohacking

In the realms of medical aesthetics and biohacking, NAD+ holds significant importance. It supports DNA repair, regulates circadian rhythms, and promotes cellular energy production through its role in the mitochondrial function. As we age, levels of NAD+ naturally decline, which has been linked with various aging-related conditions. This understanding has led to growing interest in NAD+ supplementation as a potential anti-aging intervention.

Enhancing levels of NAD+ may improve skin health by bolstering cellular energy and rejuvenation processes that can mitigate the effects of aging on the skin's appearance. Moreover, it plays a part in sirtuin activation—a group of proteins known to influence aging and inflammation—making it a cornerstone topic in anti-aging skincare discussions.

How Biohackers Utilize NAD+

Biohackers often seek ways to optimize their biological processes and enhance their quality of life through self-experimentation with lifestyle changes and supplements like NAD+. Increasing bodily concentrations of this coenzyme might contribute to improved mental clarity, better physical performance, enhanced recovery from exercise, and overall wellness.

Some popular methods biohackers use include IV infusions, oral supplements, patches, or creams containing precursors like nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) that the body can convert into NAD+. Elysium Health is one company that has developed products aimed at boosting NAD+ levels for health optimization.

The Science Behind Skin Care and Cosmetics Involving NAD+

The cosmetic industry also looks at NAD+'s potential benefits for skin care. Products such as serums or creams may feature ingredients designed to enhance cellular communication thanks to the coenzyme's properties. Companies like OneSkin develop topical products specifically formulated with peptides meant to boost NAD+ levels in the skin.

Research suggests that increased availability of NAD+ could help protect against oxidative stress—one major factor contributing to premature skin aging—and aid in repairing damaged DNA within skin cells. Consequently, cosmetics integrating strategies to elevate endogenous levels or applying it topically are emerging trends within beauty science focused on promoting youthful skin through cellular health.


Continued research into NAD+, its impact on longevity and aesthetics along with innovative approaches for supplementation could provide exciting advancements in medical aesthetics and biohacking communities alike.

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Book your appointment with Nancy Park, RN, BSN
Nancy Park, RN, BSN
Certified Aesthetic Nurse